Methylenetetrahydrofolate reductase C677T polymorphism in Iraqi patients with ischemic stroke
نویسندگان
چکیده
منابع مشابه
Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese.
Hyperhomocyst(e)inemia has been identified as an independent risk factor for atherosclerotic and thromboembolic diseases such as coronary artery disease, cerebral artery disease, and venous thrombosis. Recently, the alanine/valine (A/V) gene polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR), one of the key enzymes that catalyzes the remethylation of homocysteine, was reported. Th...
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Several epidemiological studies have examined the relationship of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with hyperuricemia. However, the results were controversial. We therefore conducted a large cross-sectional study (2,219 subjects) and an updated meta-analysis by combining previous studies (9,502 subjects) to provide more empirical evidence for the association. A...
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Background: Psoriasis is a multigenic and multifactorial dermatological disease linked to cardiovascular diseases. Increased levels of homocysteine in patients with psoriasis have been demonstrated in many studies. The most frequently investigated genetic defect that plays a role in homocysteine metabolism is single point substitution (C to T) located on the 677th nucleotide of the methylenetet...
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Homocysteine may play a causal role in cognitive decline. The authors analyzed the 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T genotype, a correlate of plasma homocysteine levels, among 6,653 participants in the Study of Osteoporotic Fractures, a community-based, prospective cohort study of older women in four US states. During the years 1986-1998, the authors assessed whether the di...
متن کاملMethylenetetrahydrofolate reductase gene polymorphism in Indian stroke patients.
BACKGROUND AND AIMS In view of the prevailing controversy about the role of Methylenetetrahydrofolate reductase (MTHFR) C677T mutation in stroke and paucity of studies from India, this study has been undertaken to evaluate MTHFR C677T gene polymorphism in consecutive ischemic stroke patients and correlate these with folic acid, homocysteine (Hcy) and conventional risk factors. SETTINGS AND DE...
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ژورنال
عنوان ژورنال: Neurology India
سال: 2009
ISSN: 0028-3886
DOI: 10.4103/0028-3886.57821